Thursday, March 9, 2017

In a study that appeared on Monday in Biological Psychiatry, scientists from the Universities of California and North Carolina, with several other universities in the United States and Canada, report a strong correlation between abnormal distribution of cerebrospinal fluid in infants and later development of autistic symptoms.

“The more extra-axial CSF present at six months, the more severe the autism symptoms when the kids were diagnosed at 24 months of age,” said first author Dr. Mark Shen, a postdoctoral fellow at the University of North Carolina.

The study covered 343 children examined aged six months, twelve months, and twenty-four months, 221 of whom had older siblings with autism. Children with higher than usual volumes of cerebrospinal fluid in the subarachnoid space — the area just around the brain — were more likely to be diagnosed with autism later in life, with a strong correlation in the high-risk group. Ultimately, cerebrospinal volume was able to provide an early diagnosis of probably ASD in high-risk children with 70% accuracy. The six-month-old babies who later went on to a diagnosis of autism had an average of 18% more CSF by volume than those who were not so diagnosed. This built on the findings of a 2013 study that covered only 55 children.

Researchers said it is not clear whether a large amount of cerebrospinal fluid actually causes autism or not. While studies have shown that cerebrospinal fluid, once thought to act solely as a cushioner and shock absorber for the brain, can influence the way neurons grow, Shen speculated that the large amount of fluid may itself be a symptom: “We believe that extra-axial CSF is an early sign that CSF is not filtering and draining when it should. The result is that there could be a buildup of neuro-inflammation that isn’t being washed [a]way.”

Currently, coauthor David Amaral said, children are not diagnosed with autism spectrum disorders until they are old enough for their behavior to change, usually at two or three years old. Researchers said these findings could be used to develop an early diagnostic system usable when the patient is as young as six months old.

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Wednesday, March 15, 2006

Washington, D.C. —When you mix a shopping cart, six team members, bar hopping and bonus points for schmoozing bar hostesses and sabotaging your enemies, you get the annual Washington, D.C. Idiotarod race. On Saturday, this bizarre fund raising event, which originated in San Francisco 13 years ago, pitted teams of “sleds” together to race from bar to bar in Washington, D.C.’s fashionable Dupont Circle and Adams Morgan neighborhoods. Each “sled” consists of a “borrowed” shopping cart and six human dogs to pull the cart. Points are given for originality, the best time and best sabotage of another sled.

The race is held to benefit the Arlington Food Assistance Center and is organized by Ellen Shortill and Kristen Heatherly. Their organization, called “SMASHED” or “Society for Mature Adults Seeking to Help, Entertain and Donate”, takes the position that donating small amounts many times ultimately benefits the smaller charities. Said Shortill, “Our goal is simply to have fun and raise money for those charities that don’t really get any attention.”

The race this year consisted of 22 teams. Although team “Save NOLA” got to the last bar first, teams can win bonus points for (among other things) flirting with bar hosts and hostesses at any of the five bars along the route. The route is approximately 3 miles long, and each team is required to spend at least 20 minutes in each bar. Heatherly noted that “it doesn’t matter who got here first, ultimately its the team with the most credits and the best time that wins.”

Unique among the participants are brothers Pete and Chris Magnuson who are attempting to get on the 10th edition of Amazing Race on CBS. Their team called “Pick Pete and Chris” ran through the streets with t-shirts hawking their website and their fervent desire to be chosen for the next edition of the television show.

“Its not really about who wins, its that we get to have a blast and raise some money,” said Shortill. The charity event raised about $500 and various canned goods for the food pantry.

Saturday, January 15, 2011

An amphibious vehicle belonging to the United States Marines capsized and sank to the floor of the Del Mar boat basin, California at 1130 PST (1930 UTC) resulting in one death and three injures.

Three instructors and three students were conducting driver training when the vehicle capsized and sank, trapping them inside. Three injured individuals were transported to hospital and two were uninjured. The deceased Marine was rescued at around 1415 PST and was transported to hospital where he was pronounced dead at 1447 PST. Oxygen was being pumped into the vehicle for hours in an attempt to keep the Marine alive.

Captain Daniel J. Thomas revealed that “There will be a thorough investigation into this mishap that occurred.” He continued, “[there will be] reports that come, lessons learned in terms of preventing anything like this from happening.” Major Thomas said that training would not be stopped, but “We’re going to take a look at this and the commander will then make a decision before anything goes back into place to make sure any safety briefing that need to be given are conducted.”

The identity of the dead Marine has not yet been revealed; the family have yet to have been notified.

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Sunday, November 1, 2009

At least two people have been killed in a landslide at the Playa de los Gigantes beach on the Spanish island of Tenerife. The Foreign and Commonwealth Office has confirmed the information today.

The victims were both women. One of them was identified as a 34-year-old woman from the southern part of the island. The other was identified as Marion Auril O’Hara, a 57-year-old woman from the United Kingdom. The collapsing of the cliff, which was on a small beach and stretched 130 feet (40 metres), occurred at around 1600 GMT on Sunday.

Initially, it was believed that there were six people trapped underneath the cliff. 150 rescue workers dug with picks and shovels, and continued digging for over four hours. However, the search was later scaled down, with the Senior Civil Guard Officer saying that “we now believe that these two women were the only victims.”

Howard Williams, who was on holiday from the United Kingdom in the area, told Sky News Online that “police were aware the cliff was dangerous for days, but the only thing they put in place was a bit of builder’s tape.”

Thursday, January 24, 2013

A group of researchers published a paper about their discovery of a new species of Madagascar mermaid skink lizards last December. The species is the fourth forelimbs-only terrestrial tetrapods species known to science, and the first one which also has no fingers on the forelimbs.

The species was collected at Marosely, Boriziny (French: Port-Bergé), Sofia Region, Madagascar. The Sirenoscincus mobydick name is after the existing parent genus, and a sperm whale from the 1851 novel Moby-Dick by Herman Melville.

This week, Wikinews interviewed one of the researchers, French zoologist Aurélien Miralles, about the research.

((Wikinews)) What caused your initial interest in Madagascar lizards?

Aurélien Miralles: Well, I would say that since I am a child I am fascinated by the biodiversity of tropical countries, and more especially by reptiles. I did a PhD on the evolution and systematics of skink lizards from South America. Then, I get a Humboldt grant to do a postdoc in Germany, at the Miguel Vences Lab, in order to study Malagasy skinks. Madagascar being a fabulous hotspot for reptiles (and not only for reptiles actually), it was a very nice opportunity. Professor Vences proposed me to associate our complementary fields of expertise: he is expert in herpetology for Madagascar, and I am expert in skinks lizards (family Scincidae). It was a very fruitful experience, and many other results have still to [be] published.

((WN)) How was the new species discovered?

AM: By a very funny coincidence actually. In 2010, I went to Madagascar for a long trip through the south of the island, in the semi-arid bush for collecting lizards and snakes samples. Then, during the last days, just before coming back to Germany, I have visited by coincidence the zoological collection of the University of Antananarivo. In that place, I found an old jar of ethanol with two weird little specimens previously collected by a student who didn’t realize it was something new. Being expert on skinks, I immediately recognised it was something very probably new, very different from all the other known species.

((WN)) What does “Sirenoscincus” stand for?

AM: I am not the author of the genus name Sirenoscincus. This genus name was already existing. It has been described by Sakata and Hikida (two Japanese herpetologists). “Sireno” means mermaid. “Scincus” means skinks, a group of little lizards on which I am particularly focusing my studies. So, Sirenoscinus means “mermaid skink”, in reference to [the] fact it has forelimbs but no hindlimbs.

((WN)) How deep underground do the lizards live?

AM: Hard to answer this question because nothing is known on the ecology of this species. But more reasonably, we can hypothesize, by comparison to similar species of skinks, that it is probably living just under the sand surface, [a] few centimeters deep, probably no more, or below [a] rock, leaf litter, or piece of dead wood.

((WN)) What do the lizards eat?

AM: Again, by analogy, I would say most likely small invertebrates (insects, larvae, worms etc…).

((WN)) What equipment was used during the research?

AM: Classic equipment (microscope) and also a state-of-the-art device: a micro CT-scan. It is a big device producing [a] 3D picture of the internal structure without damaging the specimen. It is actually very similar to the scanner used in human medicine, but this one is specially designed for small specimens. Otherwise, I am currently studying the DNA of this species and closely related species in order to determine its phylogenetic position compared to other species with legs, in order to learn more about the evolutionary phenomena leading to limb loss.

((WN)) There are several news sources that have a photo of the species. Is it a photo as seen in a CT-scan?

AM: No, this picture showing a whitish specimen on a black background is not a CT-scan. It is a normal photograph of the collection specimen preserved in alcohol (the one that was in the jar). You can see the complete of picture (including CT-scan 3D radiography, drawing…) in the original scientific publication.

((WN)) Do you know when the newly discovered mermaid skink species was put into the jar? Do you have its photo (of the jar)?

AM: No, I have no picture of the jar. The specimen has been collected in November 2004.

((WN)) What were the roles of the people involved in the research? What activity was most time-consuming?

AM: As first investigator, I did most of the work…and the longest part of the work was to examine closely related species in order to do comparisons…and also to check the complete bibliography related to this topic and to write the paper.

Mrs Anjeriniaina is the student who […] collected the specimen a couple of years ago.

Mrs Hipsley and Mr Müller learnt me how to use the CT-scan, and helped me concerning some point relative to internal morphology. Mr Vences helped me as supervisors. Additionally, all of them have corrected the article, and gave me many relevant advices and corrections, thus improving the quality and the reliability of the paper.

((WN)) Did you get in touch with an external entity to get the new species officially recognised?

AM: No. In zoology, it is only needed to publish the description of a new species (and to give it a name) in a scientific journal, and to designate a holotype specimen (= specimen that will be the official reference for this species), to get this new species “officially” recognised by the scientific community. That does not mean that this new species is “correct” (it might be invalidated by subsequent counter-studies), but that means that this discovery and the new name of [the] species are officially existing.

((WN)) Are there any further plans on exploring the species habitat and lifestyle?

AM: No, not really for the time being, because ecology is not our field of expertise. But other studies (including molecular studies) are currently in progress, in order to focus on the phylogenetic position and the evolution of this species.